| 货号 | 包装规格 | 操作 |
|---|---|---|
| 946001-500MG | 500 mg |
3-马来酰亚胺丙酸NHS酯是一种双功能交联剂，可用于有效的生物结合。NHS酯与伯胺反应，而马来酰亚胺基团选择性地结合硫醇，形成稳定的硫醚键。非常适合蛋白质标记、抗体-药物结合物（ADC）和靶向生物分子修饰。高反应性和特异性确保了蛋白质组学、药物递送和分子成像的可靠结果。
The maleimide-thiol chemistry of 3-Maleimidopropionic acid NHS ester is pivotal in ADC development, enabling precise conjugation of cytotoxic drugs to monoclonal antibodies. Its high specificity ensures selective binding to cysteine residues, while the stability of the resulting thioether bonds enhances drug delivery efficiency to target cancer cells, reducing off-target toxicity. PMID 26387744 3-Maleimidopropionic acid NHS offers high reactivity and selectivity, reducing off-target interactions and ensuring efficient conjugation. It is widely used in proteomics and biomolecular research for precise protein labeling, and its unique properties make it a trusted choice for pharmaceutical and biotechnology applications. PMID 28771339,PMID 15348806
| 英文名称 | 3-(Maleimido)propionic acid-NHS ester |
| CAS 号 | 55750-62-4 |
| 经验分子式 | C11H10N2O6 |
| 分子量 | 266.21 |
| NACRES | NA.21 |
| InChI | InChI=1S/C11H10N2O6/c14-7-1-2-8（15）1 - 2（7）6-5-11（18）19-13-9（16）3-4-10（13）17/h1-2H，3-6H2 |
| SMILES字符串 | O=C1C=CC（=O）N1CCC（=O）ON2C（=O）CCC2=O |
| 含量测定 | ≥95% |
| 形态 | 固体 |
| 颜色 | 白色至米色 |
| 储存温度 | 2-8°C |
| 质量等级 | 100 |
| 包装规格（货号 946001-500MG） | — |
