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Sigma-Aldrich BODIPY-FL-C12,≥98%(HPLC)

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Sigma-Aldrich BODIPY-FL-C12,≥98%(HPLC)

Sigma-Aldrich BODIPY-FL-C12,≥98% (HPLC)
SIGMA-ALDRICH授权代理合成砌块
CAS 号 158757-79-0品牌 Sigma-Aldrich类目 实验室试剂 / 合成砌块更新日期 2026-10-27

规格与货号

货号包装规格操作
SML4395-1MG1 mg
SML4395-5MG5 mg

产品概述

≥98%(HPLC)

生化/生理作用

BODIPY-FL-C12 is a fluorescent fatty acid analog, resemble the length of C16 FA such as palmitic acid, designed for real-time visualization of lipid metabolism in living cells. Structurally, a C12 alkyl chain directs the molecule into cellular fatty acid transport pathways, while the core BODIPY fluorophore provides exceptionally bright and photostable green fluorescence (λex/λem ≈ 505/515 nm). Following rapid cellular uptake, BODIPY-FL-C12 is esterified by acyl-CoA synthetase in the endoplasmic reticulum and subsequently trafficked for robust, irreversible accumulation within the neutral lipid core of lipid droplets. This metabolic trapping mechanism generates a high signal-to-noise ratio, enabling high-resolution tracking of fatty acid uptake, transport, and storage dynamics. Its proven utility in live-cell imaging, flow cytometry, and in vivo models like C. elegans supplants traditional endpoint assays. BODIPY-FL-C12′s low cytotoxicity and high cell permeability make it an essential tool for dynamically investigating metabolic regulation in obesity, diabetes, and cancer research.

技术规格

英文名称BODIPY-FL-C12
CAS 号158757-79-0
经验分子式C23H33BF2N2O2
分子量418.33
UNSPSC12352200
含量测定≥98%(HPLC)
形态粉末
储存条件避免光照
颜色红色至深紫色
溶解性DMSO: 2 mg/mL,清澈
储存温度-10 到 -25°C
质量等级100
包装规格(货号 SML4395-1MG)—
包装规格(货号 SML4395-5MG)—

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货号可以省略点号搜索吗?
可以。如 1.2300.1001,输入 12300 或 123001001 均可检索。

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