![Sigma-Aldrich 3-(7-(tert-Butoxycarbonyl)-2-ethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-3-yl)propanoic acid hydrochloride](/img/sigma/112008-1.webp)
| 货号 | 包装规格 | 操作 |
|---|---|---|
| 920657-50MG | 50 mg |
3-(7-(tert-Butoxycarbonyl)-2-ethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-3-yl)propanoic acid hydrochloride is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Developed in partnership with ComInnex.
入口：构建用于靶向蛋白质降解的PROTAC ®降解剂生物结合技术交联剂聚焦：用于靶向蛋白质降解的降解剂构建模块
此系列中的类似连接器：920568 920657 ENAH 38 A2 CCD 6 AC 5372910424
| 英文名称 | 3-(7-(tert-Butoxycarbonyl)-2-ethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-3-yl)propanoic acid hydrochloride |
| 经验分子式 | C16H26ClN3O4 |
| 分子量 | 359.85 |
| UNSPSC | 12352106 |
| NACRES | NA.22 |
| InChI key | OYHWWEYTVJATKM-UHFFFAOYSA-N |
| SMILES字符串 | C2CCN（C（OC（C）（C）C）= O）CC2 = N1.Cl，其中C（C）（C））= O） |
| 形态 | 粉末和块 |
| 反应适用性 | 试剂类型：连接器 |
| 官能团 | 羧酸 |
| 储存温度 | 2-8°C |
| 质量等级 | 100 |
| 包装规格（货号 920657-50MG） | 50 mg |
