| 货号 | 包装规格 | 操作 |
|---|---|---|
| SCP0193-1MG | 1 mg |
Matrix Metalloproteases (MMPs) belongs to the zinc metalloprotease family M10.PMID 16405877 They are zinc-dependent, calcium-containing hydrolases.
Matrix Metalloproteases (MMPs) are involved in extracellular matrix (ECM) degradation.PMID 16405877 MMPs regulate cellular and disease processes. They are implicated in processes such as cell proliferation, migration, differentiation, angiogenesis, anti-inflammatory response, vasoconstriction, apoptosis and host defense. Dysregulation of MMP is associated with arthritis, ulcers, encephalomyelitis and cancer.
肽MCA-Lys-Pro-Leu-Gly-Leu-DNP-Dpa-Ala-Arg-NH 2或FS-6是几种基质金属蛋白酶（MMP）的荧光底物。FS-6是公认的MMP底物FS-1的水溶性修饰形式，其中赖氨酸残基已被添加到FS-1的N-末端。已报道所得FS-6产生对几种MMP具有改进的动力学性质的肽，包括MMP-1、MMP-8、MMP-13和MMP-14。这种MMP底物也被描述为锌金属蛋白酶肿瘤坏死因子-α转化酶的特别有用的底物。（TACE或ADAM-17）。FS-6可用于测量组织培养条件下的金属蛋白酶活性，例如，在活细胞表面原位。PMID 15113693
| 英文名称 | MMP Substrate |
| 经验分子式 | C55H80N16O16 |
| 分子量 | 1221.32 |
| UNSPSC | 12352200 |
| NACRES | NA.32 |
| 含量测定 | ≥95%（HPLC） |
| 形态 | 冻干 |
| 成分 | 肽含量，≥75% |
| 储存条件 | 避免光照 |
| 储存温度 | −20°C |
| 包装规格（货号 SCP0193-1MG） | 1 mg |
