| 货号 | 包装规格 | 操作 |
|---|---|---|
| SCT247 | 1 mg |
DNA/RNA G-quadruplexes (G4s) are four-stranded nucleic acid structures that fold from numerous guanine (G)-rich sequences found in the genome and transcriptome. Their abundance and localization in critical regulatory regions make them key players in genetic diseases (cancer, neuropathology), but not only (e.g., viral infection). For this reason G4s have garnered intense interest as potential targets in different therapeutic areas
The BioTracker™ MultiTASQ G-quadruplex G4 cell probe is optimized for detection (1) and/or the isolation of G4s (2,3). MultiTASQ utilizes the template-assembled synthetic G-quartets (TASQ) (4) concept as a biomimetic ligand for G-quadruplexes, a design which results in high specificity for folded G4.
References
1. Nat. Chem. 2021, 13(7): 626-633
2. ACS Chem Biol. 2021, 16(5): 905-914
纯度：通过HPLC、HNMR、LC-MS和元素分析确认> 98%。
与BG4抗体相比，MultiTASQ可更好地检测与核周粗糙ER区域相关的核糖体RNA-G4。MultiTASQ是一种炔基化探针，可通过点击化学进行无背景检测，适用于G4捕获化学沉淀和点击成像应用。MultiTASQ与活细胞孵育兼容。BioTracker MultiTASQ G4细胞探针是一种独特设计的，G4检测和分析的通用工具。
冻干。白色固体。
将BioTracker BioCyTASQ G-quadruplex G4细胞探针储存在-20 ° C下，干燥并避光
使用点击化学荧光检测细胞和组织中的核酸G4四链体
| 英文名称 | BioTracker MultiTASQ G-Quadruplex (G4) Cell Probe |
| NACRES | NA.52 |
| UNSPSC | 41106514 |
| 包装 | 1 mg小瓶 |
| 制造商/商标 | Millipore |
| 增长方式 | N/A |
| 技术 | DNA测序：适宜; RNA提取：适宜;核酸检测：适宜 |
| 检测方法 | 荧光测定 |
| 运输状态 | 干冰 |
| 储存温度 | −20°C |
| 质量等级 | 100 |
| 包装规格（货号 SCT247） | 1 mg |
