| 货号 | 包装规格 | 操作 |
|---|---|---|
| P6993-1VL | 1 vial |
Protein Phosphatase 2A1 (PP2A1) belongs to the PP2A family and comprises trimeric A, B and C subunits.PMID 10677363 PPA2 enzymes are serine/threonine phosphatasesPMID 11996003 and exist as several isoforms.PMID 24653673
蛋白质磷酸酶2A 1在蛋白质印迹分析前已用于处理人成纤维细胞PMID 10733583.
Protein Phosphatase 2A is a cytoplasmic protein, which colocalizes with microtubule proteins and is involved in the dephosphorylation of the tau protein and oncoprotein 18. Protein Phosphatase 2A1 (PP2A1) binds to polymerized microtubule proteins and may be targeted by tubulin in modulating phosphatase activity.PMID 10677363 PP2A1 is implicated as a growth suppressor and is associated with dysregulation in cancer.PMID 11996003 It also regulates cell cycle, RNA splicing differentiation, and signal transduction.PMID 11996003 PP2A dysfunction is correlated to the tau protein deregulation in Alzheimer′s disease pathophysiology.PMID 24653673 Protein Phosphatase 2A1 is a divalent cation-dependent protein serine/threonine phosphatase implicated as a growth suppressor and is associated with dysregulation in cancer.
50 mM Tris-HCl溶液，pH 7.0，含有14 mM 2-巯基乙醇、1 mM苯甲脒、0.1 mM PMSF、1 mM EDTA和50%甘油
在pH 7.0和30 °C条件下，一个单位每分钟将从32 P标记的磷酸化酶A中释放1.0纳摩尔的磷酸盐。
| 英文名称 | Protein Phosphatase 2A1 bovine |
| UNSPSC | 12352204 |
| NACRES | NA.54 |
| MDL 号 | MFCD00241719 |
| 生物来源 | 牛 |
| 含量测定 | ≥90%（SDS-PAGE） |
| 形态 | 解决方案 |
| 比活性 | ≥1500单位/mg蛋白质 |
| 分子量 | 192千道尔顿 |
| 包装 | 1 μg小瓶 |
| 运输状态 | 干冰 |
| 储存温度 | −70°C |
| 质量等级 | 200 |
| 包装规格（货号 P6993-1VL） | 1 vial |
