



| 货号 | 包装规格 | 操作 |
|---|---|---|
| SML2982-5MG | 5 mg | |
| SML2982-25MG | 25 mg |
≥95%(HPLC)
线粒体靶向活性氧(ROS)-清除短杆菌肽S(GS)-氮氧化物,体外和体内对抗氧化应激损伤的功效。
XJB-5-131 is a mitochrondria-targeted electron-/reactive oxygen species (ROS)-scavenging GS-nitroxide composed of 4-amino-TEMPO and the gramicidin S (GS)-derived peptide Boc-Leu-Ψ[€-CH=CH]-D-Phe-Pro-Val-Orn(Cbz). XJB-5-131 offers 39-fold greater anti-ferroptotic efficacy than JP4-039 in HT-1080 cultures (100% viability with 200 nM XJB-5-131 against ferroptosis induction by 10 μM FINO2) and is a widely employed mitochondrial antioxidant both in cultures (typical range: 40 nM-2 μM) and in animal dissease models in vivo (e.g. 2 mg/kg via ip.or iv.; mice & rats).
| 英文名称 | XJB-5-131 |
| CAS 号 | 866404-31-1 |
| 经验分子式 | C53H80N7O9 |
| 分子量 | 959.24 |
| UNSPSC | 12352200 |
| NACRES | NA.77 |
| InChI | 1S/C53H80N7O9/c1-35(2)30-40(56-50(66)69-51(5,6)7)27-26-39(31-37-20-14-12-15-21-37)48(64)59-29-19-25-43(59)46(62)58-44(36(3)4)47(63)57-42(24-18-28-54-49(65)68-34-38-22-16-13-17-23-38)45(61)55-41-32-52(8,9)60(67)53(10,11)33-41/h12-17,20-23,26-27,35-36,39-44 |
| InChI key | 公司简介 |
| SMILES字符串 | CC(C)(C)OC(N[C@@H](CC(C)C)/C=C/[C@H](CC1=CC=CC=C1)C(N2CCC[C@H]2C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(OCC3=CC=CC=C3)=O)C(NC4CC(C)(N([O])C(C)(C4)C)C)=O)=O)=O)=O)=O |
| 含量测定 | ≥95%(HPLC) |
| 形态 | 膜或粉末 |
| 颜色 | 白色至米色 |
| 储存温度 | 2-8°C |
| 质量等级 | 100 |
| 包装规格(货号 SML2982-5MG) | 5 mg |
| 包装规格(货号 SML2982-25MG) | 25 mg |