![Sigma-Aldrich Pomalidomide-2,6-diazaspiro[3.3]heptane，≥95.0%](/img/sigma/179017-1.webp)
| 货号 | 包装规格 | 操作 |
|---|---|---|
| 934232-50MG | 50 mg |
≥95.0%
Pomalidomide-2,6-diazaspiro[3.3]heptane Hydrochloride is a functionalized Cereblon ligand used for development of protein degrader building blocks. Contains a terminal amine group, allowing rapid conjugation of carboxyl containing linkers. A basic building block for development of a protein degrader library.
Technology Spotlight:
Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
小分子靶向蛋白质降解可编程寡核苷酸PROTAC（O ′ PROTAC）对DNA结合蛋白的破坏：有效靶向LEF1和ERG小分子PROTACS：蛋白质降解的新方法靶向蛋白质降解：从化学生物学到药物发现连接体长度对PROTACs活性的影响
| 英文名称 | Pomalidomide-2,6-diazaspiro[3.3]heptane |
| CAS 号 | 2226301-50-2 |
| 经验分子式 | C18H18N4O4 |
| 分子量 | 354.36 |
| UNSPSC | 12352200 |
| NACRES | NA.21 |
| InChI | 1S/C18H18N4O4/c23-14-4-3-13(15(24)20-14)22-16(25)11-2-1-10(5-12(11)17(22)26)21-8-18(9-21)6-19-7-18/h1-2,5,13,19H,3-4,6-9H2,(H,20,23,24) |
| InChI key | ZJRIIJGHSAJWMI-UHFFFAOYSA-N |
| SMILES字符串 | O = C1N（C2CCC（NC2 = O）= O）C（C3 = CC = C（N4CC5（CNC5）C4）C = C31）= O |
| 配体 | pomalidomide |
| 含量测定 | ≥95.0% |
| 形态 | 粉末或晶体 |
| 颜色 | 灰白色至浅黄色 |
| 储存温度 | 2-8°C |
| 质量等级 | 100 |
| 包装规格（货号 934232-50MG） | 50 mg |
![Sigma-Aldrich 5-Methyl-4-oxo-N-o-tolyl-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamide](/img/sigma/115257-1.webp)
