| 货号 | 包装规格 | 操作 |
|---|---|---|
| C3743-5MG | 5 mg |
>98%（HPLC），固体
CI 976 has been used as an acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor:
to analyze its anti-hepatitis C virus (HCV) activity in Huh7.5.1 cells PMID 29074218to treat Neuro-2a cells to test its effect on plasma membrane integrated density of α4-SEPβ2 or α6-SEPβ2β3 nicotinic acetylcholine receptors (nAChRs)PMID 26961950to study its effects on the anti-angiogenic activity of pyripyropenes in human umbilical vein endothelial cellsPMID 19571395
CI-976是肝和肠酰基辅酶A：胆固醇酰基转移酶（ACAT）的强效和特异性体外抑制剂。
CI-976, a new trimethoxy fatty acid anilide, is a potent and specific inhibitor of liver and intestinal acyl coenzyme A; cholesterol acyltransferase (ACAT) in vitro. CI-976 decreased non-high density lipoprotein (HDL)-cholesterol and increased HDL-cholesterol in rats with pre-established dyslipidemia. High performance gel chromatographic separation of plasma lipoproteins also revealed that CI-976, but not CL 277,082, lowered low density lipoprotein (LDL)-cholesterol and elevated HDL-cholesterol.
| 英文名称 | CI 976 |
| CAS 号 | 114289-47-3 |
| 经验分子式 | C23H39NO4 |
| 分子量 | 393.56 |
| NACRES | NA.77 |
| UNSPSC | 51111800 |
| MDL 号 | MFCD00869662 |
| InChI key | 博茨瓦纳-乌夫法伊萨-北 |
| SMILES字符串 | （C）（C）（C）（= O）不饱和脂肪酸 |
| InChI | 1 S/C2, 3 H39 NO 4/C1-7-8-9-10-11-12-13-14-15- 2,3（2，3）22（25）24-21-19（27-5）16-18（26-4）17-20（21）28-6/小时16 - 17小时，7- 15小时，1- 6小时 |
| 含量测定 | >98%（HPLC法） |
| 形态 | 固体 |
| 溶解性 | 二甲基亚砜：>10 mg/mL;水：不溶物<2 mg/mL |
| 储存温度 | 2-8°C |
| 质量等级 | 100 |
| 包装规格（货号 C3743-5MG） | 5 mg |
