| 货号 | 包装规格 | 操作 |
|---|---|---|
| C5688-10UG | 10 μg |
90 - 110 μ g/mL的PBS溶液，pH 7.2，≥ 90%（SDS-PAGE）
Complement factor D is a serine protease essential for the activation of the alternative pathway in the complement system. Research of complement factor D has revealed that a self inhibitory loop is responsible for switch from a resting to active state. Additionally, recent research has linked a complement factor D gene, single nucleotide polymorphism (SNP) rs3826945, with age-related macular degeneration (AMD). In these AMD cases there was a significant increase in plasma complement factor D concentration, even though previous research has shown no association between complement factor D SNP genes and AMD.
补体因子D是一种丝氨酸蛋白酶，与胰凝乳蛋白酶结构相似，在补体级联反应中，因子D与活化的补体成分C3复合物中的补体因子B裂解，与脂肪组织中表达的脂蛋白酶相同。
用于检测HBSAg、HCV、HBC、梅毒和HIV-1/HIV-2的源血浆
有关补体途径的更多信息，请访问www.sigma-aldrich.com/enzymeexplorer
| 英文名称 | Complement factor D from human plasma |
| CAS 号 | 37213-56-2 |
| UNSPSC | 12352202 |
| NACRES | NA.61 |
| MDL 号 | MFCD00166417 |
| 生物来源 | 人血浆 |
| 含量测定 | ≥90%（SDS-PAGE） |
| 形态 | 液体 |
| 集中 | 90-110 μg/mL的PBS溶液，pH 7.2 |
| UniProt 登录号 | P00746 |
| 运输状态 | 干冰 |
| 储存温度 | −70°C |
| 质量等级 | 200 |
| 基因信息 | 人体...计算流体力学（1675） |
| 包装规格（货号 C5688-10UG） | 10 μg |
