Sigma-Aldrich 1,5,6,7-四氢-4H-吲哚-4-酮，百分之九十八

产品概述

Iodination of 1,5,6,7-tetrahydro-4H-indol-4-one using 1-chloromethyl­-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetra­fluoroborate) yields α-iodo derivative as the main product.

应用领域

1,5,6,7-Tetrahydro-4H-indol-4-one may be used in the preparation of:
4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carbonitrilemethyl 2-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)acrylate3-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)propanenitrilepotent and orally active 5-HT1A agonists, (R)-(+)- and (S)-(-)-1-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H-benz[e]indol-8-amines

抗肿瘤剂沙柄藻素A的合成反应物通过C-H插入反应制备5-四氢苯并吲哚β-酮酯和三环四氢苯并吲哚作为鸟苷酸环化酶抑制剂的三环吲哚和二氢吲哚衍生物的反应物通过Pd催化的分子内C-H键官能化制备稠合吡咯并吲哚的反应物GB/T14549 - 1993（卤苄基）吡咯类铑卡宾不对称C-H插入后科普重排消除对映选择性制备芳基烯基吲哚类化合物的反应物

技术规格