Sigma-Aldrich Aldehyde functionalized hyaluronic acid，功能化程度~20%

产品概述

Hyaluronic acid (HA) is an important component of the natural extracellular matrix which plays a vital role in various cellular and tissue functions. It represents some unique properties such as excellent gel-forming properties and chemical modification ability through hydroxyl and carboxyl groups that make them potentially useful for their application in Tissue engineeringPMID 23399155. Partially oxidized hyaluronate (OHA) containing two highly aldehyde groups in the repeating unit of HA. The dialdehyde groups of OHA are capable of reductive coupling with primary amines and thus can be used in a wide range of chemical modifications of HA as hydrogel for tissue engineering applicationsPMID 32929113 and regenerative medicinePMID 32824101 drug delivery applications

应用领域

羟基磷灰石（HA）具有促进细胞迁移、血管生成、细胞存活和增殖的作用，因此在许多生物医学领域得到了广泛的应用。醛功能化的羟基磷灰石（HA）可用于开发组织工程、再生医学、生物打印和药物递送应用的水凝胶。

产品特点

与伯胺的偶联能力生物相容性功能化天然聚合物促进多种细胞和组织功能

技术规格