| 货号 | 包装规格 | 操作 |
|---|---|---|
| 8.51095.0100 | 100 g | |
| 8.51095.0500 | 500 g | |
| 8.51095.1000 | 1 kg |
PyOxim [1] is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents.
Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents
Literature references
[1] R. Subiros-Funosas, et al. (2010) Org. Biomol. Chem., 8, 3665.
介导PyBOP、TBTU和HCTU的上级效率偶联介导低外消旋或差向异构化偶联理想用于片段缩合和环肽合成，因为试剂不会引起胍基化在DMF和NMP中具有优异的溶解性
颜色（目视检查）：白色至类白色物质外观（目视检查）：粉末鉴别（IR）：通过检测含量测定（HPLC，面积%）：≥ 99. 0%溶解度（1 mmol，溶于2 ml DMF）：明显可溶
| 英文名称 | PyOxim |
| CAS 号 | 153433-21-7 |
| 经验分子式 | C17H29F6N5O3P2 |
| 分子量 | 527.38 |
| UNSPSC | 12352126 |
| NACRES | NA.22 |
| MDL 号 | MFCD18643381 |
| SMILES字符串 | F[P-](F)(F)(F)(F)F.[P](=[N+]3CCCC3)(N2CCCC2)(N1CCCC1)O\N=C(\C(=O)OCC)/C#N |
| InChI | 1S/C17H29N5O3P.F6P/c1-2-24-17(23)16(15-18)19-25-26(20-9-3-4-10-20,21-11-5-6-12-21)22-13-7-8-14-22;1-7(2,3,4,5)6/h2-14H2,1H3;/q+1;-1/b19-16+; |
| InChI key | RDDWDVLFMPFUBDV-PXMDEAMVSA-N |
| 产品系列 | 新比奥肯® |
| 含量测定 | ≥99.0%（HPLC） |
| 形态 | 粉末 |
| 反应适用性 | 反应类型：偶联反应 |
| 制造商/商标 | 新比奥肯® |
| 应用 | 肽合成 |
| 储存温度 | -10 到 -25°C |
| 质量等级 | 300 |
| 包装规格（货号 8.51095.0100） | 100 g |
| 包装规格（货号 8.51095.0500） | 500 g |
| 包装规格（货号 8.51095.1000） | 1 kg |
