Sigma-Aldrich 13C-Short Chain Fatty Acids Stool Mixture，适用于质谱分析

产品概述

Short chain fatty acids (SCFAs) are saturated fatty acids with less than 6 carbons. SCFAs are produced in the gut by microbial fermentation of dietary fibers.PMID 27259147 The most important and researched SCFAs are Acetate (Ac), propionate (Pr) and butyrate (Bu).PMID 3678950 SCFAs are predominantly found in the colon and cross the intestinal epithelium to the blood stream. SCFAs were found to be beneficial and effective in prevention of obesity, Non-alcoholic fatty liver disease and insulin resistance.PMID 30670819PMID 25559882
The concentration of SCFAs in Stool is varied from subject to subject in dependence to the experiment parameters. The Average concentration for Acetate, Propionate and Butyrate 30, 10, 10 μM respectively.

¹³C-SCFAs can serve in various applications:
spiking the mixture to track sample preparation errors.QC sample, to exclude run to run variations and to normalize the runs.Calibration curve to quantify SCFAs in Stool samples.

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