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Sigma-Aldrich Ghrelin rat,冻干粉

SIGMA-ALDRICH

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Sigma-Aldrich Ghrelin rat,冻干粉

Sigma-Aldrich Ghrelin rat,lyophilized powder
SIGMA-ALDRICH授权代理生化试剂
品牌 Sigma-Aldrich类目 实验室试剂 / 生化试剂更新日期 2026-10-27

规格与货号

货号包装规格操作
G8903-.1MG0.1 mg

产品概述

Ghrelin is a gut-brain orexigenic peptide that functions in hunger signaling. This peptide is prominently synthesized by stomach and transported to brain. However, a specific subset of hypothalamic neurons also produces this peptide.PMID 24830778 It is expressed in gastrointestinal tract, hypothalamic arcuate nucleus, pituitary, kidney, liver, heart, lung and adipose tissue This peptide is composed of 28 amino acids, and its Ser3 residue is N-octanoylated.PMID 26467127

应用领域

已将Ghrelin大鼠用于腹腔内注射和大鼠中的显微注射以研究其对乳糜泻、PMID 25532955和被动回避学习(PAV)和空间学习的作用,PMID 19463714 PMID 19828130还将其用于大鼠脑室内注射,以研究其对青霉素诱导的大鼠癫痫样活动的影响。PMID 19552953

生化/生理作用

Ghrelin acts as a ligand for G-protein coupled receptor, GHS-R1A (growth hormone secretagogue receptor), and controls energy utilization and feeding. This peptide is involved in enhancing the value of rewarding foods, drugs and alcohol.PMID 24830778 In rats with diabetes, the expression of ghrelin increased as a result of cachexia.PMID 26467127 In rats with ovariectomy, the expression of this peptide decreased in the endometrium.PMID 24979506 This peptide controls cognitive functions and has neuroprotective roles in neurodegenerative disorders. In cultured cortical neuronal networks, ghrelin increases the rate of synapse formation and activity development.PMID 24742241

孤儿生长激素促分泌素受体的内源性配体,刺激垂体中生长激素的释放。

物理形态

0.1% TFA水溶液冻干

其他说明

从0.1% TFA的H2O溶液中冻干

技术规格

英文名称Ghrelin rat
UNSPSC51111800
NACRESNA.32
MDL 号MFCD02687544
形态冻干粉
颜色白色
溶解性1%乙酸:1 mg/mL;水:1 mg/mL
UniProt 登录号Q9QYH7
储存温度−20°C
质量等级200
基因信息鼠...格尔(59301)
包装规格(货号 G8903-.1MG)0.1 mg

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