


| 货号 | 包装规格 | 操作 |
|---|---|---|
| F7807-50UG | 50 μg |
重组体,在大肠杆菌中表达,≥90%(SDS-PAGE)
Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma PMID 16157291.
PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways PMID 12432932.
一个单位定义为在含有250 μM NADPH和25 μM 9,10-菲醌的50 mM KPO 4(pH 7.2)中,于37°C下每分钟产生1 μmol NADP所需的酶量
| 英文名称 | Prostaglandin F Synthase human |
| CAS 号 | 55976-95-9 |
| MDL 号 | MFCD00900598 |
| UNSPSC | 12352204 |
| NACRES | NA.54 |
| 重组 | 在大肠杆菌中表达 |
| 描述 | 含有一个C-末端六组氨酸标签 |
| 含量测定 | ≥90%(SDS-PAGE) |
| 形态 | 液体 |
| 比活性 | ≥0.4 μmol/mg蛋白质 |
| 分子量 | 约37 kDa |
| NCBI 登录号 | NP_003730 |
| 运输状态 | 干冰 |
| 储存温度 | −70°C |
| 质量等级 | 200 |
| 基因信息 | 人... AKR 1C 3(8644) |
| 包装规格(货号 F7807-50UG) | 50 μg |