


| 货号 | 包装规格 | 操作 |
|---|---|---|
| SRE0024-100UG | 100 μg |
甘油醛-3-磷酸脱氢酶(GAPDH)定位于细胞质,但可根据细胞条件转移到细胞核。它是一种含有相同链的四聚体。编码GAPDH的基因定位于人类染色体12 p13。PMID 25882840
人甘油醛-3-磷酸脱氢酶已被用作硫化氢处理的阳性对照,以检测蛋白质靶标的巯基化。
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-phosphate, which is a critical energy-yielding step in carbohydrate metabolism. It binds to several proteins including actin, tubulin, amyloid precursor, polyglutamine peptides, DRPLA (dentatorubral-pallidoluysian atrophy) and huntingtin.PMID 16492755 Phosphorylated GAPDH associates with cytoskeletal elements and controls microtubule dynamics in the early secretory pathway.PMID 11724794 GAPDH is also a component of the functional GAIT (interferon-?-activated inhibitor of translation) mRNP (messenger ribonucleoprotein).PMID 15479637 GAPDH expression is dysregulated during melanoma progression.
本产品是在大肠杆菌中表达的重组人GAPDH,带有N-末端组氨酸标签,预测分子量为37,984 Da。本产品从含有稳定剂的缓冲溶液中冻干。
替代编号:CAS登记号9001-50-7
在pH 7.6和25 °C条件下,在与3-磷酸甘油磷酸激酶(3-PGK)偶联的系统中,一个单位每分钟将1.0 μ mol 3-磷酸甘油酸还原为D-甘油醛3-磷酸
| 英文名称 | Glyceraldehyde-3-phosphate dehydrogenase human |
| UNSPSC | 12352204 |
| NACRES | NA.54 |
| 重组 | 在大肠杆菌中表达 |
| 比活性 | ≥ 80单位/mg蛋白质 |
| 储存温度 | −20°C |
| 质量等级 | 200 |
| 包装规格(货号 SRE0024-100UG) | 100 μg |