| 货号 | 包装规格 | 操作 |
|---|---|---|
| SRP8045-10UG | 10 μg |
CD40L (cluster of differentiation 40 ligand), a member of TNF (tumor necrosis factor) superfamily, is a membrane bound protein.PMID 25418472 This protein is predominantly expressed transiently by activated CD4+ T cells either as a cell-surface molecule or a secreted multimer protein. Activated B cells, certain DC (dendritic cell) subsets, platelets, and smooth muscle cells also express this protein.PMID 24928989
CD40L (cluster of differentiation 40 ligand) interacts with its receptor CD40 which in turn helps mediate the interaction between APCs (antigen presenting cells) and lymphocytes. Activated platelets produce CD40L which then participates in multiple processes such as endothelial cell reactions, formation of germinal center, T-helper cell priming, and cytotoxic T-cell activation. Platelets are also involved in the pathogenesis of asthma through CD40L where they inhibit the production of regulatory T-cells and promote polarization of T-helper cells.PMID 25418472 Studies in mice show that this protein confers protection against influenza virus, though in a CD4+ T cell independent manner.PMID 24928989
从PBS中冻干。
用100 μL去离子水复溶。
小鼠CD 40 L（aa 115-260）在N-末端融合至小鼠ACRP 30无头（aa 18-111）和FLAG ® -标签。
| 英文名称 | CD40L, Soluble mouse |
| NACRES | NA.32 |
| UNSPSC | 12352200 |
| 生物来源 | 小鼠 |
| 重组 | 在CHO细胞中表达 |
| 标签 | FLAG®标签 |
| 含量测定 | >95%（SDS-PAGE） |
| 形态 | 冻干 |
| 分子量 | 35-40 kDa |
| 包装 | 每包10 μg |
| 储存条件 | 避免反复冻融 |
| 杂质 | <0.01 EU/μ g内毒素，检测 |
| UniProt 登录号 | P27548 |
| 运输状态 | 湿冰 |
| 储存温度 | −20°C |
| 基因信息 | 鼠. Cd 40 lg（21947） |
| 包装规格（货号 SRP8045-10UG） | 10 μg |
