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Sigma-Aldrich Sestrin 2 human,重组,在杆状病毒感染的Sf 9细胞中表达,≥35%(SDS-PAGE)

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Sigma-Aldrich Sestrin 2 human,重组,在杆状病毒感染的Sf 9细胞中表达,≥35%(SDS-PAGE)

Sigma-Aldrich Sestrin 2 human,recombinant, expressed in baculovirus infected Sf9 cells, ≥35% (SDS-PAGE)
SIGMA-ALDRICH授权代理生化试剂
品牌 Sigma-Aldrich类目 实验室试剂 / 生化试剂更新日期 2026-10-21

规格与货号

货号包装规格操作
SRP0412-50UG50 μg

产品概述

Sestrin 2 (SESN2), a highly conserved protein,PMID 33359748 is a member of a family of anti-aging proteins called the sestrins.PMID 33359262 Human SESN2 (hSESN2) contains three subdomains, such as SESN-A, SESN-B, and SESN-C.PMID 31867002 The SESN2 gene is mapped to human chromosome 1p35.3.PMID 19609442

应用领域

Sestrin 2 human may be used to study its role on blood brain- barrier (BBB) stabilization after moderate and severe hypoxic- ischemic (HI) injuries in neonatal rats.PMID 27425892

生化/生理作用

Sestrin 2 (SESN2) plays a vital role in modulating cellular stress response and oxidant defense.PMID 33359748 It plays a regulatory role in energy metabolism, cell fate, liver diseases, inflammation, and carcinogenesis.PMID 31867002 This novel anti-aging protein aids to maintain mitochondrial activities and enhance mitochondrial health. Since SESN2 is capable of protecting tissues from oxidative stress and mitochondrial dysfunction caused by ischemia or reperfusion (I/R), it may be a promising therapeutic target in hepatic regeneration.PMID 33359262

技术规格

英文名称Sestrin 2 human
NACRESNA.32
UNSPSC12352200
生物来源人类
重组在杆状病毒感染的Sf 9细胞中表达
含量测定≥35%(SDS-PAGE)
形态水溶液
分子量55 kDa
包装50 μg/包
NCBI 登录号NM_031459
UniProt 登录号P58004
运输状态干冰
储存温度−70°C
基因信息人... SESN 2(83667)
包装规格(货号 SRP0412-50UG)50 μg

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