| 货号 | 包装规格 | 操作 |
|---|---|---|
| 86541-5G | 5 g |
Testosterone propionate is the esterified form of testosterone that is most commonly used in clinical applications for the treatment of hypogonadism, oligospermia, and impotence.PMID 3782423 17β-hydroxyl group of propionate is esterified to get this form. It is a fast and short-acting form when compared to enanthate and cypionate forms, which are long-acting esters more commonly used in androgen replacement therapies.
Testosterone propionate has been used:
to determine the effect of testosterone on the uptake of certain amino acids, such as isoleucine and α-(methylamino)isobutyric acidPMID 21606113in a study to understand the effects of testosterone on brain aromatase activity in neonatal quail brainPMID 20147858for testosterone treatment of Celf1 knockout mice in a study to investigate the upregulation of aromatase activity in association with hypogonadismPMID 26169831to investigate the ontogeny of aromatase-expressing neurons in Japanese quail brainPMID 22628012to study the effects of in vivo administration of testosterone propionate on fluid reabsorption in the efferent ducts of rat.PMID 16130270
睾酮是男性循环中主要的雄激素，主要由睾丸产生。少量由肾上腺分泌。它由睾丸间质细胞中的胆固醇产生。睾酮代谢为二氢睾酮，二氢睾酮是一种与细胞质受体蛋白结合的强效雄激素，形成复合物。该复合物被激活并转运到细胞核中。在那里它触发了几种生物学反应。它主要在胚胎发生和青春期参与雄性表型的发育。PMID 325393 PMID 6895207
可能实行销售限制
| 英文名称 | Testosterone propionate |
| CAS 号 | 57-85-2 |
| 经验分子式 | C22H32O3 |
| 分子量 | 344.49 |
| UNSPSC | 12352211 |
| NACRES | NA.21 |
| EC 号 | 200-351-1 |
| MDL 号 | MFCD00003653 |
| InChI key | PDMMFKSKQVNJMI-BLQWBTBKSA-N |
| InChI | 1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1 |
| SMILES字符串 | [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC |
| 基因信息 | human ... AR(367), CYP17A1(1586) rat ... Ar(24208) |
| 机构 | 根据欧洲药典检测 |
| 形态 | 固体 |
| 药物管制 | USDEA附表IIIN;受CDSA监管-无法从Sigma-Aldrich Canada获得 |
| 包装规格（货号 86541-5G） | 5 g |
